Antidiarrhoeal Activities of Lime (Citrus aurantiifolia) Extract in Experimentally-Induced Diarrhoea Model
نویسندگان
چکیده
This study investigated the effects of Lime on Diarrhoea in Wistar rats. A total 60 rats were procured and randomly divided into 3 groups 20 animals each for three t-test models. The twenty healthy diarrhoea model fasted 6 hours prior to experiment but allowed free access water. 5 4 experiment. Established antidiarrhea models followed. test received various doses (97.65mg/kg, 195.3mg/kg, 390.6mg/kg) Citrus aurantiifolia juice extract; whereas positive controls Loperamide (2.5mg/kg) negative distilled water (1ml/kg). administration was done once daily 15 days, faeces animal collected 5th, 10th 15th day. result this showed that medium high dose has an anti-diarrhoeal effect castor oil-induced over repeated a minimum days as it prolonged onset diarrhoea, decreased frequency defecation gastrointestinal transit time shows demonstrates significant activity can be used anti-diarrhoea agent.
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ژورنال
عنوان ژورنال: Biology, Medicine & Natural Product Chemistry
سال: 2023
ISSN: ['2089-6514', '2540-9328']
DOI: https://doi.org/10.14421/biomedich.2023.121.305-313